Different active substances and medicines containing them, can affect the fertility of women and the fertility symptoms, which are used mainly in the use of methods of natural family planning. The purpose of this application is to provide an overview of the effects and impacts, which may be used various drugs, respectively. active ingredients for sexuality and fertility signs.Liga couple couple in Slovak Republic is a civic organization that teaches symptotermálnu method (STM) of natural family planning (NFP) and promotes non-contraceptive lifestyle. Spreading ecological breastfeeding, family support activities and helps build marital relations.